Technically untrue.
It was originally a Run Run option.
Today its a Run Run Pass Option.
The Pass part of the option was actually an "accident" that Alex Smith executed at Utah because of a blown defensive assignment.
The basic fundamentals of the RPO are about a numbers advantage in the run game.
Oh, I've seen that video before.
Notice how Myers said "101".
And he was only talking about himself and Alex Smith.
As to the true origin of the RPO, you can go back a long time ago.
The Veer Offense that Bill Yeoman ran at UH back in the 70s was not even the first one with the run run (keeper) pass option concept in it.
The RPO that Sweeny runs at Clemson can be run as a full-on system that encompasses a whole lot more than what we saw in that video, and in the pro game on Sunday.
It may have two backs in the backfield, or a HB/TE, or a receiver in motion either in front or behind the QB (sometimes you may end up with 4 guys in the backfield.)
At other time, you may see them line up in the pistol formation with the RB behind the QB as a change up.
The QB keeper that Urban Myers mentioned is really just a change up as far as the Clemson's offense is concerned (and a small change up at that, if the OC wants to).
They could use all that motion to throw a screen pass to the RB or a tunnel screen to the receiver.
And with the motion of the receiver I had mentioned above, it can be a jet sweep, or the receiver can throw the ball himself.
They build a full playbook out of it, but they can always run the spread offense just like what we used to see on Sunday in years past (before the RPO becomes a novelty anew in the last few years) in conjunction with it.