I think some of you were pretty close.
To dispel one myth, he's actually a pretty decent passer, this is not like last year where he couldn't hit water if you fell out of a boat. He is top 5 in QBR, with a completion percentage in the mid 60's, and only 5 picks on the year with 1900 yards, and 12 TD'S through the air. It is not as simple as making him throw, Belichek tried and he got burned.
As to how much is stop our offense, I think you have to try something nobody else did. There is one glaring weakness on our offense that can be exploited. Our interior o line is average at best. Our left tackle is one of the top three tackles in the game, and we have a young guy on the right side who is also very good. So with that being said, I think teams should try doing double a gap blitzs. Have the ends keep contain have your two defensive tackles take on a guard and then do a double a gap blitz on the center. You're going to throw off the timing of all the bootlegs, and the triple option game. And it's going to leave you one on one in man coverage, but as has been pointed out the only great pass-catcher we have is our tight end Mark Andrews.
Marquise Brown can burn you deep, but he's 165 lb. have your best corner play bump and run coverage on him, and give him a good jam at the line to disrupt the route. Have your next best cover man cover Mark Andrews, and then play zone.
someone also brought up a great point, is to keep them are Jackson off the field. He is lightning in a bottle, the more opportunities you give him he will eventually make you pay. If I were Bill O'Brien, I would be making sure to have my best pass-catching running back on the field, and just so long as he can kind of run between the tackles he's going to be hard to defend if you go no-huddle.
Our secondary is starting to come together, and we have the most talented secondary in the NFL. That said our interior linemen are very beatable, and we're not the greatest at covering with our linebackers. If you were to exploit angle and wheel routes with a running back off of play action in a no-huddle, I think you can find some success.
In my opinion this game boils down to 2 things and 2 things only. Our offensive line and your offensive line. if our offensive line can move your defensive line, and give the offense enough time to beat the blitz it could be a long day. On the flip side if the double a gap blitz works and you can smother the receivers for three or four seconds allowing the rush to get home, I think you're going to have some success with a spy on Jackson.
If your offensive line can keep Watson clean, and force our secondary to cover will Fuller and DeAndre Hopkins, I could also see you guys having a very good day. I'm not terribly concerned about Fuller, but DeAndre Hopkins is almost unguardable. The catch he made this year by pinning the football to the inside of his leg, and then catching it without dropping it on the turf, just one of the greater catches I've seen this year. You can't defend against things like that. The only thing you can do is make sure the quarterback doesn't have time to find him.
Just like we were a nightmare stylistic matchup against New England, I think our two worst stylistic matches left on the schedule are Houston and San Fran. I'm really not even that concerned about San Fran. Just like New England they've been beating up on cans. This game is going to be an amazing game to watch. If either quarterback gets loose, both teams will be in trouble. If they both get loose at the same time we're in for a real treat.