And if Watson or Hopkins or Tunsil or any top-end defender blows out their knee, will It be worth it?
That could happen in practice. Injuries are part of the game and you deal with them as they come.
There's still advantages to be gained by putting yourself in position to do so. How are you going to feel if the Chargers beat KC next week and we lose because we treated it like a preseason game?
Granted, I'm not real sure the Texans chances against the Titans, for a 3rd time in 4 weeks, are that much better than going ahead and playing Buffalo, BUT, there's still a chance we could play Pittsburgh, which I like those chances a lot, and you avoid Baltimore for at least another week. Maybe. Hell, I even like our chances winning our 1st ever game in Foxborough better than facing Bills, followed by Ravens.
I get the concern with injury, but still think you've got to try and gain every advantage you can.