If you're looking for an optimistic benchmark for moving up that far then look at the Julio Jones trade. Falcons gave up #27, their 2nd, their 4th, next year 1st, and next year 4th for #6 overall. That's not bad because they kept their original 3rd and the next year 2nd & 3rd. Those 1-3 round picks are where you find impact players so they landed Jones and still kept 3 out of 5 impact picks.
However, after what the Redskins did, I don't see many teams biting on an Atlanta type offer when there is a top QB still on the table. Just to move from #6 to #2 the Redskins gave up #6, their 2nd, their next year 1st, and the year after 1st. That's three 1st's and a 2nd to move up 4 spots. To move from #22 to #3 you're looking at giving up #22, your 2nd, your 4th, your next year 1st, your next year 2nd, your year after 1st, and your year after 3rd. You're likely looking at giving up three 1st's, two 2nd's, and a couple 3/4's.
That is a monumental amount of picks. You better be 100% damn sure that this guy you're moving for is the real deal. The only QB prospect I've been that confident about is Luck and, as much as I like Goff, he's not Luck.