Wow - talk about your open ended topics.
My 2 bits - I would go with an outside approach. Use alot of outs, timing patterns and flats passes, screens, off-tackle runs, play action and pitches. I would try to use the speed of my offense to gain 4-6 yards per play by keeping to the outside and it should be easy. I would a majority of the time try to key the play to the weakside or long side of the field on run plays to give the RB room to make something happen and for slants, timing patterns and outs the time to develop. It's a little modified west coast style of using short to moderate passes to the TE, running backs out of the backfield and hands receivers to setup downfield plays. I would run a 3 receiver set mainly [Johnson, Gaffney, Bradford] along with Miller every down to offset the defense and keep them from Keying on miller everytime he comes in the game. WE need our TE to be very active and involved in the passing game along with our receivers and backs to open up the field for the receivers and the long routes later IMO.
Running game - alot of quick pitches to the outside and in/outof the tackles on occasion to the sidelines. I would switch DD and Morrency every other running down in the game. I would alwyas push them towards the weak/long side to give them room to run and then switch to a different back to keep the legs fresh.
I would use the offenses outside push to make the defense have to beat us by rolling their coverage outside. I push them and drive the defense down the field w/outside slants, screens, rollouts to setup the inside run stuff and across the middle TE and rb out of the backfield plays all day long. Miller should have at least 7-10 rec per game and would open up more field for AJ to play in also down the field for the long balls.
I dont like alot of changing formations, but would rather them keep with a few formations and change plays at the line to keep the defense guessing. Come to the line with 2 calls a pass and run call giving the offense something of a pre-audible call so to speak. Show one look and then shift a back or receiver or TE to a new spot in the same formation and run an inverted play. one down after another to put the defense on it's heels by having 2 plays ready to go. Mix in 2 min drill formations once in a while to put speed on the offense and keep the defense tired and chasing us all day long.